ABSTRACT
Introduction: Type 2 diabetes mellitus (DM) is the most lifestyle risk factor for cognition. Regular treatment and managementof Type 2 DM could prevent the onset and progression of cognitive impairment. Cognitive decline associated with DM mayinfluence one’s ability to perform self-care and affect glycemic control.Aim: Our prospective observational study aimed to analyze the cognitive impairment using a mini-mental status examination(MMSE) in patients with Type 2 DM.Materials and Methods: This prospective observational study was conducted to analyze the cognitive impairment using MMSEin patients with Type 2 DM. A total of 50 patients diagnosed with Type 2 diabetes were included in the study. All the demographicand laboratory investigation data so obtained was tabulated and was analyzed statistically, and results were discussed.Results: Of 50 patients, 26 patients were male and 24 patients were female. Based on the age group, 11 patients were in theage group below 40 years, 21 patients between 40 and 50 years, 16 patients between 51 and 60 years, and 2 patients >60years. Based on the duration of Type 2 diabetes, 16 patients had <5 years and MMSE score of 24.28 and 34 patients had >5years and MMSE score of 22.14. Based on cognitive impairment, 44 patients had mild cognitive impairment and 6 patientshad moderate cognitive impairment.Conclusion: From this study, we concluded that the duration of Type 2 DM and level of HbA1c affect the cognitive status ofthe individuals. A greater understanding of the mechanisms linking Type 2 DM and cognitive impairment may facilitate thedevelopment of new ways for the treatment of cognitive impairment.